======================== General information ======================== The following tutorials will show you how to analyze a sample dataset with SPM. You will begin by learning the fundamentals of fMRI preprocessing, and then proceed to create a statistical model to estimate brain activity in response to different conditions. After learning about group-level results and how to script your analysis. This course will show you how to analyze an fMRI dataset from start to finish. We will begin by **exploring your dataset** by inspecting the anatomical and functional images for each subject. We will then **preprocess the data**, which removes noise and enhances the signal in the images. Once the images have been preprocessed, we will create a model representing what we think the :ref:`BOLD signal `, a measure of neural activity, should look like in our images. During **model fitting** we compare this model with the signal in different areas of the image. This model fit is a measure of the strength of the signal under different conditions - for example, we can take the difference of the signal between conditions of the experiment to see which condition leads to a larger BOLD response. Once a model has been created for each subject and the BOLD response has been estimated for each condition, we can do any kind of group analysis we like: Paired t-tests, between-group t-tests, interactions, and so on. The goal of this course is to calculate a simple within-subjects contrast between two conditions, and test whether it is significant across subjects. You will also learn how to create figures showing whole-brain analyses, similar to what you see published in the neuroimaging journals. .. figure:: img/bric_xlarge_2100102.jpg